Autoimmunity, the phenomenon by which the body's immune system attacks itself instead of invading organisms, is a factor in a wide range of currently incurable diseases from rheumatoid arthritis to juvenile diabetes. The recent explosion of interest in pharmacological methods of controlling the immune system has focused on T-cells, the central players in the immune system. This book not only covers the established drug, cyclosporin, and the brand new immunosuppressive drug FK 506, but also includes sections on T-cell monoclonal antibodies and alternative approaches