Crystal-clear and easy-to-read, this popular text focuses on the essential pathophysiology, diagnoses, and management of the most common clinical situations. The addition of many new radiographs enhances understanding of disease mechanisms; and an abundance of new tables and displays adds more visual interest to this exciting new edition.The Fourth Edition provides expanded coverage of ambulatory medicine; more information on coronary artery disease, including lipids and cholesterol; expanded coverage of Lyme disease; and an expanded chapter on tuberculosis. Thirteen new chapters in the Fourth Edition cover gonadal dysfunction and menopause; chemotherapeutic treatment; lung cancer; gastrointestinal cancer; breast tumors; prostate cancer; gonadal tumors; treatment of infectious diseases in the ambulatory setting; demyelinating diseases; dementia; neuromuscular diseases; depression; and anxiety.